Tyrosols and derivatives
Medchemexpress LLC 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide | 745833-23-2 | MFCD11616590 | 99.7% | 404.32 g/mol | C19H12F4N4O2 | 1 ML
VX-702 is a selective small-molecule inhibitor of p38α mitogen-activated protein kinase (MAPK) used in research to probe p38α-mediated signaling and inflammatory pathways. It demonstrates higher potency for p38α than p38β and has been evaluated in preclinical and clinical studies for anti-inflammatory applications. Supplied for laboratory research use only.
- Selective p38α MAPK inhibitor with approximately 14-fold selectivity over p38β.
- Suitable for studying inflammatory signaling and cytokine regulation.
- Provided as a 10 mM solution in DMSO for ready-to-use applications.
- High purity (product page lists 99.69%), appropriate for biochemical assays.
- Molecular weight 404.32 g/mol and formula C19H12F4N4O2.
- Good solubility in DMSO (≥ 42 mg/mL) for convenient stock preparation.
- For research use only; not intended for human or veterinary use.
Apexbio Technology LLC VX-702 479543-46-9; 745833-23-2 25mg
VX-702 is a small-molecule inhibitor targeting p38 mitogen-activated protein kinase (MAPK) also known as MAPK14 It is designed to inhibit p38 MAPK thereby regulating cellular responses to cytokine signaling and various stressors VX-702 exerts its biological activity primarily through ATP-competitive inhibition In experimental models VX-702 demonstrates potent inhibition with reported IC50 values ranging from 4 to 20 nM Based on these pharmacological properties VX-702 holds research potential in the study of p38 MAPK-dependent pathways platelet storage lesions and renal excretion mechanisms
Betaxolol hydrochloride, Tocris Bioscience™
CAS: 63659-19-8 Molecular Formula: C18H30ClNO3 Molecular Weight (g/mol): 343.892 InChI Key: CHDPSNLJFOQTRK-UHFFFAOYSA-N Synonym: betaxolol hydrochloride,betaxolol hcl,betoptima,kerlone,betoptic,kerlon,lokren,betaxolo hydrochloride,betoptic s PubChem CID: 107952 ChEBI: CHEBI:643228 IUPAC Name: 1-[4-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(propan-2-ylamino)propan-2-ol;hydrochloride SMILES: CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl